Practice Resources

Amsterdam Placental Workshop Group Consensus Statement

A recent (2016) paper outlining consensus guidelines for gross and microscopic placenta examination including recommended sampling, preferred terminology, and current grading/staging schemes for lesions. Click here to read more. 

College of American Pathologists Guidelines for Examination of the Placenta

The original (1997) consensus guidelines for gross and microscopic placental examination, including clinical indications for submission and reporting templates. Click here to download the guidelines. 

Neuroblastoma Tumor Atlas

The Informatics & Communication Committee, on behalf of the SPP, would like to introduce the first of several digital pediatric atlases - the Atlas of Neuroblastic Tumors. The atlas represents an annotated walkthrough neuroblastic tumors using examples from the central review files is now available to visitors to the SPP website.

Members are encouraged to visit the atlas to review classic images and descriptions of different neuroblastic tumors. We hope this provides a valuable reference and teaching tool for residents and fellow trainees. 

The Informatics & Communications Committee would like to thank the members of the International Neuroblastoma Pathology Committee for contributing this atlas.

Click here to download a bookmarked PDF of the Neuroblastoma Tumor Atlas.

Placental Pathology Papers:

  • Khong TY, Mooney EE, Ariel I, Balmus NC, Boyd TK, Brundler MA, Derricott H,Evans MJ, Faye-Petersen OM, Gillan JE, Heazell AE, Heller DS, Jacques SM, KeatingS, Kelehan P, Maes A, McKay EM, Morgan TK, Nikkels PG, Parks WT, Redline RW,Scheimberg I, Schoots MH, Sebire NJ, Timmer A, Turowski G, van der Voorn JP, van Lijnschoten I, Gordijn SJ. Sampling and Definitions of Placental Lesions:Amsterdam Placental Workshop Group Consensus Statement. Arch Pathol Lab Med. 2016Jul;140(7):698-713. doi: 10.5858/arpa.2015-0225-CC. Epub 2016 May 25. PubMedPMID: 27223167. https://www.ncbi.nlm.nih.gov/pubmed/27223167 
  • Langston C, Kaplan C, Macpherson T, Manci E, Peevy K, Clark B, Murtagh C, Cox S, Glenn G. Practice guideline for examination of the placenta: developed by the Placental Pathology Practice Guideline Development Task Force of the College of American Pathologists. Arch Pathol Lab Med. 1997 May;121(5):449-76. PubMed PMID: https://www.ncbi.nlm.nih.gov/pubmed/9167599
  • Pinar H, Sung CJ, Oyer CE, Singer DB. Reference values for singleton and twin placental weights. Pediatr Pathol Lab Med. 1996 Nov-Dec;16(6):901-7. PubMed PMID:9025888. https://www.ncbi.nlm.nih.gov/pubmed/9025888 
  • Pinar H, Stephens M, Singer DB, Boyd TK, Pflueger SM, Gang DL, Roberts DJ,Sung CJ. Triplet placentas: reference values for weights. Pediatr Dev Pathol.2002 Sep-Oct;5(5):495-8. Epub 2002 Sep 4. PubMed PMID: 12202997. https://www.ncbi.nlm.nih.gov/pubmed/12202997
  • Redline RW, Faye-Petersen O, Heller D, Qureshi F, Savell V, Vogler C; Society for Pediatric Pathology, Perinatal Section, Amniotic Fluid Infection NosologyCommittee. Amniotic infection syndrome: nosology and reproducibility of placentalreaction patterns. Pediatr Dev Pathol. 2003 Sep-Oct;6(5):435-48. PubMed PMID:14708737. https://www.ncbi.nlm.nih.gov/pubmed/14708737 
  • Redline RW, Boyd T, Campbell V, Hyde S, Kaplan C, Khong TY, Prashner HR,Waters BL; Society for Pediatric Pathology, Perinatal Section, Maternal Vascular Perfusion Nosology Committee. Maternal vascular underperfusion: nosology andreproducibility of placental reaction patterns. Pediatr Dev Pathol. 2004May-Jun;7(3):237-49. Epub 2004 Mar 17. PubMed PMID: 15022063. https://www.ncbi.nlm.nih.gov/pubmed/15022063 
  • Redline RW, Ariel I, Baergen RN, Desa DJ, Kraus FT, Roberts DJ, Sander CM.Fetal vascular obstructive lesions: nosology and reproducibility of placentalreaction patterns. Pediatr Dev Pathol. 2004 Sep-Oct;7(5):443-52. Epub 2004 Jul30. PubMed PMID: 15547768. https://www.ncbi.nlm.nih.gov/pubmed/15547768 

Stillbirth/Autopsy Pathology Papers:

  • Dudley DJ, Goldenberg R, Conway D, Silver RM, Saade GR, Varner MW, Pinar H,Coustan D, Bukowski R, Stoll B, Koch MA, Parker CB, Reddy UM; Stillbirth ResearchCollaborative Network. A new system for determining the causes of stillbirth.Obstet Gynecol. 2010 Aug;116(2 Pt 1):254-60. doi: 10.1097/AOG.0b013e3181e7d975.PubMed PMID: 20664383; PubMed Central PMCID: PMC3832680.https://www.ncbi.nlm.nih.gov/pubmed/20664383 
  • Genest DR, Singer DB. Estimating the time of death in stillborn fetuses: III. External fetal examination; a study of 86 stillborns. Obstet Gynecol. 1992Oct;80(4):593-600. PubMed PMID: 1407878. https://www.ncbi.nlm.nih.gov/pubmed/1407878 
  • Genest DR. Estimating the time of death in stillborn fetuses: II. Histologicevaluation of the placenta; a study of 71 stillborns. Obstet Gynecol. 1992Oct;80(4):585-92. PubMed PMID: 1407877. https://www.ncbi.nlm.nih.gov/pubmed/1407877 
  • Genest DR, Williams MA, Greene MF. Estimating the time of death in stillbornfetuses: I. Histologic evaluation of fetal organs; an autopsy study of 150stillborns. Obstet Gynecol. 1992 Oct;80(4):575-84. PubMed PMID: 1383898. https://www.ncbi.nlm.nih.gov/pubmed/1383898
  • Hansen K, Sung CJ, Huang C, Pinar H, Singer DB, Oyer CE. Reference values for second trimester fetal and neonatal organ weights and measurements. Pediatr DevPathol. 2003 Mar-Apr;6(2):160-7. Epub 2003 Jan 29. PubMed PMID: 12548377. https://www.ncbi.nlm.nih.gov/pubmed/12548377
  • Parast MM, Crum CP, Boyd TK. Placental histologic criteria for umbilical bloodflow restriction in unexplained stillbirth. Hum Pathol. 2008 Jun;39(6):948-53.doi: 10.1016/j.humpath.2007.10.032. Epub 2008 Apr 21. PubMed PMID: 18430456. https://www.ncbi.nlm.nih.gov/pubmed/18430456  

Links to Groups

The following links may be useful to those practicing or learning pediatric pathology. These listings are provided for informational purposes only. The SPP does not approve or endorse the sites listed, and the SPP is not responsible for their content. Please utilize due diligence when selecting sites for use. If you have concerns about the content on a listed site, please bring it to the attention of the SPP website editor.

Pathology Links

Related Links

Have any suggestions for related pages/links? Please contact SPP headquarters.